NFL Week 5 Odds: Does Chiefs Vs. Bills Sound Familiar?

Written By Russ Mitchell on October 6, 2021 - Last Updated on July 22, 2022
todays chief odds week 5

NFL Week 5 starts with an early-morning Sunday kickoff in London. However, a great game awaits 4,350 miles away and 11 hours later when the Buffalo Bills visit Kansas City for Sunday Night Football (SNF).

It’s a rematch of last year’s AFC Championship game when Kansas City advanced to the Super Bowl with a 38-24 win.

Buffalo at Kansas City Chiefs odds

The Chiefs are a 2.5 favorite over the Bills, as of Wednesday afternoon. Here are the latest Kansas City Chiefs odds at Iowa sportsbooks:

PointsBet betting offers for SNF

PointsBet IA is offering a $20 bonus bet for all new and current customers. All customers can tap some fun boosted markets for the Chiefs-Bills game. Options include:

  • Tyreek Hill to have 75+ receiving yards and one or more TDs.
  • Patrick Mahomes to have 300+ passing yards and Chiefs to win.
  • Josh Allen to have 250+ passing yards and two or more touchdowns.

Kansas City evened its record at 2-2 with a 42-30 win Sunday over the Philadelphia Eagles.

Patrick Mahomes completed 24-of-30 passes for 278 yards and five touchdowns. The victory helped the Chiefs rebound from back-to-back losses to the Baltimore Ravens and LA Chargers.

Andy Reid also earned his 100th win as Kansas City’s head coach in the game.

Reid told reporters:

“You’re in a profession where winning is very important, and these guys took (the losing streak) personally. They’ve had success and want to get back to doing the things they know are correct, and we weren’t doing that for a couple of weeks. We had all of these turnovers — too much. We were giving games away that way. It was important that we buckled down together and did a nice job, and that’s what happened.”

How to watch: Buffalo at Kansas City in Week 5

  • What: Buffalo (31) at Kansas City (22)
  • When: 7:20 p.m. Sunday
  • Where: Arrowhead Stadium, Kansas City
  • TV: NBC

Mahomes registered five touchdowns against the Eagles, but the scores might be harder to come by when Buffalo comes to town. The Bills have shut out two of their last three opponents, including Sunday’s 40-0 win over the Houston Texans.

Buffalo has created at least three turnovers in each of its last three games. Former Iowa Hawkeyes and current Bills defensive captain Micah Hyde told reporters:

“They come in bunches, and we know that. So, keep attacking the football.”

NFL Week 5: Schedule and viewing guide


  • 7:20 p.m.LA Rams (3-1) at Seattle (2-2) (NFL Network)

8:30 a.m. Sunday

  • NY Jets (1-3) vs Atlanta (1-3) at Tottenham Hotspur Stadium in London (NFL Network)

Sunday (noon window)

  • Green Bay (3-1) at Cincinnati (3-1)  (FOX)
  • Detroit (0-4) at Minnesota (1-3) (FOX)
  • Denver (3-1) at Pittsburgh (1-3)  (FOX)
  • Miami (1-3) at Tampa Bay (3-1) (CBS)
  • New Orleans (2-2) at Washington (2-2) (CBS)
  • Philadelphia (1-3) at Carolina (3-1) (FOX)
  • Tennessee (2-2) at Jacksonville (0-4) (CBS)
  • New England (1-3) at Houston (1-3)  (CBS)

Sunday (late window)

  • 3:05 p.m. — Chicago (2-2) at Las Vegas (3-1)  (CBS)
  • 3:05 p.m.Cleveland (3-1) at LA Chargers (3-1) (CBS)
  • 3:25 p.m.NY Giants (1-3)  at Dallas (3-1)  (FOX)
  • 3:25 p.m.San Francisco (2-2) at Arizona (4-0) (FOX)

Sunday Night Football

  • 7:20 p.m. — Buffalo (3-1) at Kansas City (2-2) (NBC)

Monday Night Football

  • 7:15 p.m. — Indianapolis (1-3)  at Baltimore (3-1)  (ESPN)
Photo by Reed Hoffmann / AP
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Russ Mitchell

Russ Mitchell has been covering news and sports in northwest Iowa since 1997, including 11 years as managing editor for one of the most acclaimed community newspapers in the state. He looks forward to keeping readers up to date on the growing sportsbook industry in Iowa.

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